TEAS science: anatomy and physiology study guide
Human anatomy and physiology is the largest piece of the TEAS science section: 18 of its 44 scored questions, according to ATI. The good news is that the questions sit at the level of an introductory course. You need the vocabulary of body orientation, the main organs of each system, what each system does, and how the systems work together. This guide walks through all of it in the order a textbook would.
Body orientation: positions, planes and cavities
Everything is described from anatomical position: standing upright, facing forward, arms at the sides, palms forward.
| Term | Means | Example |
|---|---|---|
| Superior / inferior | Toward the head / toward the feet | The heart is superior to the diaphragm |
| Anterior (ventral) / posterior (dorsal) | Front / back | The sternum is anterior to the heart |
| Medial / lateral | Toward / away from the midline | The ears are lateral to the nose |
| Proximal / distal | Closer to / farther from where a limb attaches | The elbow is proximal to the wrist |
| Superficial / deep | Toward / away from the body surface | Skin is superficial to muscle |
The sagittal plane divides the body into left and right (midsagittal: into equal halves). The frontal (coronal) plane divides front from back. The transverse plane divides top from bottom. The dorsal cavity holds the cranial cavity (brain) and the vertebral canal (spinal cord); the ventral cavity holds the thoracic cavity (lungs and heart) and, below the diaphragm, the abdominopelvic cavity.
Support and movement: skeletal and muscular systems
The adult skeleton has 206 bones. It supports and protects the body, anchors muscles, stores minerals such as calcium, and makes blood cells in red bone marrow. The axial skeleton is the skull, vertebral column and rib cage; the appendicular skeleton is the limbs plus the shoulder and pelvic girdles. Ligaments join bone to bone; tendons join muscle to bone.
There are three muscle types. Skeletal muscle is striated and voluntary. Cardiac muscle is striated, involuntary and found only in the heart. Smooth muscle is non-striated and involuntary, lining hollow organs such as the stomach and blood vessels. Skeletal muscles work in pairs: when the agonist contracts, the antagonist relaxes (the biceps flexes the elbow, the triceps extends it). Contraction happens when actin and myosin filaments slide past each other, powered by ATP and triggered by calcium.
Control: nervous and endocrine systems
The central nervous system is the brain and spinal cord; the peripheral nervous system is every nerve outside them. The peripheral system's autonomic branch runs involuntary functions: sympathetic (fight or flight: faster heart rate, dilated pupils, slowed digestion) and parasympathetic (rest and digest). A neuron receives signals through dendrites and sends them along its axon; the myelin sheath speeds conduction. The cerebrum handles thought and voluntary movement, the cerebellum coordination and balance, and the brainstem breathing and heart rate.
The endocrine system controls the body more slowly, through hormones carried in the blood. Know the pairs: the pituitary (often called the master gland) releases hormones that direct other glands; the thyroid sets metabolic rate; the pancreas releases insulin (lowers blood glucose) and glucagon (raises it); the adrenal glands release epinephrine and cortisol; the ovaries and testes release sex hormones. Most hormone levels are held steady by negative feedback.
Transport and exchange: cardiovascular and respiratory systems
Blood returning from the body enters the right atrium, passes to the right ventricle, and is pumped through the pulmonary arteries to the lungs. Oxygen-rich blood returns through the pulmonary veins to the left atrium, then the left ventricle, which pumps it out through the aorta. Arteries carry blood away from the heart and veins carry it back; the pulmonary vessels are the exception to the oxygen rule. Capillaries are where exchange with the tissues happens.
Air travels through the nose, pharynx, larynx, trachea, bronchi and bronchioles to the alveoli, where oxygen diffuses into the blood and carbon dioxide diffuses out. The diaphragm contracts and moves down during inhalation, enlarging the chest cavity and drawing air in. Breathing rate is driven mainly by carbon dioxide levels in the blood.
Processing: digestive and urinary systems
Food moves from the mouth through the esophagus, stomach, small intestine (duodenum, jejunum, ileum) and large intestine. Chemical digestion begins in the mouth with salivary amylase. Most digestion and absorption happen in the small intestine, whose villi enlarge its surface; the large intestine absorbs water. The liver makes bile, the gallbladder stores it, and bile emulsifies fats. The pancreas sends digestive enzymes into the duodenum.
The urinary system is two kidneys, two ureters, the bladder and the urethra. The working unit of the kidney is the nephron: blood is filtered at the glomerulus, and useful substances are reabsorbed along the tubule. The kidneys balance water, electrolytes and pH, and antidiuretic hormone (ADH) tells them to conserve water.
Protection and continuity: integumentary, immune and reproductive systems
The skin has an outer epidermis, a dermis with blood vessels, nerves, glands and hair follicles, and the subcutaneous layer beneath. It protects, regulates temperature by sweating and changing blood flow, senses touch and pain, and starts vitamin D production.
The immune system's first defenses are barriers such as skin and mucus. The innate response (inflammation, fever, phagocytes) is fast and general. The adaptive response is specific and has memory: B cells make antibodies and T cells attack infected cells and coordinate the response. The lymphatic system returns tissue fluid to the blood and filters it through lymph nodes; the spleen filters blood.
In reproduction, the testes produce sperm and testosterone; the ovaries produce eggs, estrogen and progesterone. Fertilization usually happens in the uterine (fallopian) tube, and the embryo implants in the uterus.
How to study A&P for the TEAS
Learn one system at a time with the same four questions: what are its organs, what does it do, what controls it, and what other system does it depend on. Then test yourself with mixed questions, because the real test jumps between systems. Build a word-part habit as you go (cardi- heart, nephr- kidney, gastr- stomach, -itis inflammation): it helps in the English vocabulary questions too. Try the anatomy and physiology practice set, then the broader science practice set.
โ Test yourself: 5 questions
Tap an answer to check it, or open the answer and rationale under each question.
Question 1 of 5 ยท Human Anatomy and Physiology
During labor, stretching of the cervix triggers oxytocin release, which strengthens contractions and causes further stretching. Which kind of control is this?
- Antagonistic control by two hormones
- Negative feedback that restores a set point
- Nervous reflex with no hormone involved
- Positive feedback that amplifies a change
Show the answer and rationale
Answer: D
Each round of contractions causes more oxytocin release, so the change grows until the baby is delivered; that is positive feedback. Negative feedback would reduce the stimulus, antagonistic control pairs opposite hormones such as insulin and glucagon, and this loop clearly involves a hormone.
๐ Learn it: Endocrine system: glands, hormones and feedback loops
Question 2 of 5 ยท Human Anatomy and Physiology
Which pair of hormones works antagonistically to regulate blood calcium?
- Insulin and glucagon
- Calcitonin and parathyroid hormone
- Antidiuretic hormone and aldosterone
- Estrogen and progesterone
Show the answer and rationale
Answer: B
Calcitonin lowers blood calcium by promoting its storage in bone, while parathyroid hormone raises it, so they oppose each other. Insulin and glucagon are the antagonistic pair for blood glucose, and ADH and aldosterone both act to conserve water rather than calcium.
๐ Learn it: Endocrine system: glands, hormones and feedback loops
Question 3 of 5 ยท Human Anatomy and Physiology
Fingerprints are formed by ridges in which layer of the skin?
- The hypodermis
- The stratum corneum alone
- The reticular layer of the dermis
- The papillary layer of the dermis
Show the answer and rationale
Answer: D
The papillary layer, the thin upper dermis, forms dermal papillae that push up the epidermis into ridges, which create fingerprints. The reticular layer is the deeper, thicker dermis of dense connective tissue, and the hypodermis lies below the skin.
๐ Learn it: Integumentary system: skin layers, functions and glands
Question 4 of 5 ยท Human Anatomy and Physiology
Shaking the head to signal "no" depends mainly on which type of joint?
- Pivot joint
- Gliding joint
- Saddle joint
- Hinge joint
Show the answer and rationale
Answer: A
Turning the head side to side is rotation of the atlas (C1) around the dens of the axis (C2), a pivot joint. Hinge joints bend in one plane, saddle joints are found at the base of the thumb, and gliding joints allow small sliding movements.
๐ Learn it: Skeletal system: bone types, axial vs appendicular, joints and bone cells
Question 5 of 5 ยท Human Anatomy and Physiology
Which pair of skin receptor and stimulus is matched correctly?
- Free nerve ending: light touch only
- Pacinian corpuscle: light touch only
- Pacinian corpuscle: deep pressure and vibration
- Meissner corpuscle: deep pressure and vibration
Show the answer and rationale
Answer: C
Pacinian (lamellar) corpuscles lie deep in the dermis and hypodermis and sense deep pressure and vibration. Meissner (tactile) corpuscles in the dermal papillae sense light touch, and free nerve endings mainly detect pain and temperature.
๐ Learn it: Integumentary system: skin layers, functions and glands
Your score: 0 of 0 ยท more โ
Mixed science sets with a rationale for every answer. No account needed.
โ Frequently asked
How many anatomy questions are on the TEAS?
ATI lists 18 scored questions in human anatomy and physiology, out of 44 scored science questions. Unscored pretest questions are mixed in as well.
Which body systems are on the TEAS?
ATI's outline lists body orientation plus the respiratory, cardiovascular, digestive, nervous, muscular, reproductive, integumentary, endocrine, urinary, immune and lymphatic, and skeletal systems.
Do I need a college A&P course before the TEAS?
It helps but is not required. The questions sit at an introductory level; a structured review of each system and plenty of mixed practice is enough for many applicants.
๐ Practice and lessons
- ๐ซTEAS anatomy and physiology practice questions10 free questions with rationales
- ๐ฏFree TEAS practice testAll four sections
- ๐Body orientation: anatomical position, planes, directions, cavities and regionsFree lesson ยท Human Anatomy and Physiology
- ๐Skeletal system: bone types, axial vs appendicular, joints and bone cellsFree lesson ยท Human Anatomy and Physiology
- ๐Nervous system and senses: CNS, PNS, neurons, brain regions, eye and earFree lesson ยท Human Anatomy and Physiology
- ๐Cardiovascular system: heart, vessels and bloodFree lesson ยท Human Anatomy and Physiology
- ๐Respiratory system: airway, gas exchange and breathingFree lesson ยท Human Anatomy and Physiology
- ๐Immune and lymphatic systems: innate, adaptive and vaccinesFree lesson ยท Human Anatomy and Physiology
Sources
- ATI: TEAS exam details (sections, questions, time, delivery options)
- ATI help: What is on the ATI TEAS Version 7?
- ATI TEAS 7 content outline (PDF)
Checked November 2026. ATI can change the exam and its policies; when a source and this page disagree, the source wins. Original text by TEAS Ready. TEAS is a registered trademark of ATI; TEAS Ready is not affiliated with or endorsed by ATI.
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